Traumatic brain injury (TBI) is a significant contributor to disability and mortality globally. According to the CDC, in 2014, an average of 155 individuals died daily from injuries involving TBI. These incidents account for roughly 30% of all injury-related fatalities in the United States. In 2010, approximately 2.5 million hospitalizations related to TBI were reported in the U.S. alone.
Hyperbaric Oxygen Therapy (HBOT) combined with intensive rehabilitation has shown to accelerate recovery from traumatic brain injury (TBI) by alleviating hypoxia and neuroinflammation while enhancing brain circulation and activity. These positive effects extend to individuals with concussions or mild brain injuries, suggesting broader implications for their treatment.
Clinical research has highlighted the following advantages of hyperbaric oxygen therapy for individuals in the recovery phase of traumatic brain injury.
Hyperbaric oxygen therapy facilitates neurological repair and regeneration in individuals recuperating from traumatic brain injury (TBI).
This research article underscores the advantages of hyperbaric oxygen therapy for individuals recovering from traumatic brain injury.
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Traumatic brain injury (TBI) poses a significant public health challenge. Despite the complexity of TBI, effective treatments have been elusive. While hyperbaric oxygen therapy (HBOT) has shown neuroprotective effects in various neurological conditions, its efficacy in treating TBI remains a topic of debate. This review examines the application of HBOT in experimental and clinical settings for TBI and explores its potential mechanisms of neuroprotection. Both early and delayed multiple sessions of low atmospheric pressure HBOT have been found to reduce intracranial pressure, enhance survival rates, and facilitate neurobehavioral recovery. HBOT’s synergistic effects include improved tissue oxygenation and cellular metabolism, as well as anti-apoptotic and anti-inflammatory actions. Therefore, HBOT holds promise as a neuroprotective strategy when combined with other therapeutic approaches for TBI patients, potentially leading to improved long-term outcomes.
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